Difference between revisions of "Gamma-Glutamylmethylamide"

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{{DISPLAYTITLE:''gamma''-Glutamylmethylamide}}
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[[File:GMA.png|250px|thumbnail|right|Gamma-Glutamylmethylamide]]
{{chembox
 
| verifiedrevid = 443832154
 
|  Name = ''gamma''-Glutamylmethylamide
 
|  ImageFile = GMA_2D_Structure.png
 
|   ImageSize = 200px
 
|   ImageName = gamma-Glutamylmethylamide
 
|   ImageFile1 = GMA3d.png
 
|   ImageSize1 = 200px
 
|  ImageName1 = gamma-Glutamylmethylamide
 
|  IUPACName =<small>(2''S'')-2-amino-5-(methylamino)-5-oxopentanoic acid</small>
 
|  OtherNames = ''N''-Methyl-<small>L</small>-glutamine; metheanine
 
| Section1 = {{Chembox Identifiers
 
|  ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
 
| ChemSpiderID = 388957
 
| PubChem = 439925
 
| KEGG_Ref = {{keggcite|correct|kegg}}
 
| KEGG = C03153
 
| InChI = 1/C6H12N2O3/c1-8-5(9)3-2-4(7)6(10)11/h4H,2-3,7H2,1H3,(H,8,9)(H,10,11)/t4-/m0/s1
 
| InChIKey = ONXPDKGXOOORHB-BYPYZUCNBU
 
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
 
| StdInChI = 1S/C6H12N2O3/c1-8-5(9)3-2-4(7)6(10)11/h4H,2-3,7H2,1H3,(H,8,9)(H,10,11)/t4-/m0/s1
 
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
 
| StdInChIKey = ONXPDKGXOOORHB-BYPYZUCNSA-N
 
| CASNo = 3081-62-7
 
|  DrugBank_Ref = {{drugbankcite|correct|drugbank}}
 
| DrugBank = DB03473
 
| ChEBI_Ref = {{ebicite|correct|EBI}}
 
| ChEBI = 58200
 
| SMILES = O=C(NC)CC[C@H](N)C(=O)O
 
}}
 
| Section2 = {{Chembox Properties
 
|  Formula = C<sub>6</sub>H<sub>12</sub>N<sub>2</sub>O<sub>3</sub>
 
|  MolarMass = 160.17 g/mol
 
|  Density = 1.211 g/mL
 
|  BoilingPtC = 427.5
 
  }}
 
}}
 
  
'''''gamma''-Glutamylmethylamide''', also known as '''GMA''', '''''N''-methyl-<small>L</small>-glutamine''', and '''metheanine''', is an [[amino acid]] found in [[green tea]],<ref name="Hypotensive-Yokogoshi">{{cite journal | author=Yokogoshi H, Kobayashi M. | title=Hypotensive effect of gamma-glutamylmethylamide in spontaneously hypertensive rats. | journal=Life Sci. | year=1998 | pages=1065–8 | volume=62 | issue=12 | pmid=9519808 | doi=10.1016/S0024-3205(98)00029-0}}</ref> which is structurally related to <small>L</small>-[[theanine]] and <small>L</small>-[[glutamine]].
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'''''gamma''-Glutamylmethylamide''', also known as '''GMA''', '''''N''-methyl-<small>L</small>-glutamine''', and '''metheanine''', is an amino acid found in green tea, which is structurally related to <small>L</small>-[[theanine]] and <small>L</small>-glutamine.
  
GMA has been shown to be an effective [[hypotensive]], more so than <small>L</small>-theanine.<ref name="Hypotensive-Yokogoshi" />
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GMA has been shown to be an effective hypotensive, more so than <small>L</small>-theanine.
  
  
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* [[Green tea]]
 
* [[Green tea]]
  
== References ==
 
{{reflist}}
 
 
{{DEFAULTSORT:Glutamylmethylamide, gamma-}}
 
 
[[Category:Amino acids]]
 
 
[[Category:Tea]]
 
[[Category:Tea]]
 
 
{{cardiovascular-drug-stub}}
 
 
[[fa:گاما-گلوتامیل‌متیل‌آمید]]
 

Latest revision as of 01:31, 8 October 2013

Gamma-Glutamylmethylamide

gamma-Glutamylmethylamide, also known as GMA, N-methyl-L-glutamine, and metheanine, is an amino acid found in green tea, which is structurally related to L-theanine and L-glutamine.

GMA has been shown to be an effective hypotensive, more so than L-theanine.


See also